Here at last, the final week of the NFL regular season. Let's dive into our Week 18 NFL Picks for NFL Sunday's meaningful matchups as we close out the final games of the NFL 2023 season.

Our first game to keep an eye on Sunday is the Jacksonville Jaguars up against the Tennessee Titans at home.

Week 18 NFL Picks: Jaguars 28 - Titans 14

This game really doesn't mean much for the Titans as they are already eliminated from the playoffs, but the Jaguars do have a lot to lose if they fumble this game. Both teams have banged up quarterbacks, with Jags QB Trevor Lawrence playing through multiple injuries as well as Titans rookie quarterback Will Levis. Jaguars backup quarterback C.J. Beathard did fairly decent in the shutout win against the Carolina Panthers last week. If they do turn to Beathard, they would likely attempt to gain a serviceable lead to close out the game and the AFC South Division Title.

Week 18 NFL Picks: NFC South

There are two games to watch pertaining to the NFC South winner. The New Orleans Saints host the Atlanta Falcons and the Carolina Panthers host the current division leaders Tampa Bay Buccaneers.

Saints 14 - Falcons 24

Panthers 10 - Buccaneers 30

Not too much into these games as the Panthers are the worst team in the NFL and the Buccaneers have played well the past few weeks, minus last week's loss to the Saints. If the Bucs win they claim the division title, but if they lose, they can lose the division to the winner of the Saints vs. Falcons game. The NFC South has been up in the air all year and continues its trend to the final Week 18. Anything can happen in these games as no team in the division has found any consistency throughout the NFL regular season.

Next we have the Chicago Bears heading to Lambeau Field to take on the Green Bay Packers.

Week 18 NFL Picks: Packers 21 - Bears 17

What if I told you history may repeat itself with the Packers, potentially losing to a division rival again to close out the season. Last year at this time the Packers faced off against the Detroit Lions in a win and in game. This Pack lost that game and the Lions dragged Green Bay down with them to playoff elimination. The Bears have stayed relatively competitive throughout the season and would love for the Packers to join in their misery. Green Bay will have a tough game ahead of them but hope to build off the momentum from last week's win against the Minnesota Vikings.

Lastly, we have a matchup that was anticipated since the beginning of the season. It was determined that the Miami Dolphins and the Buffalo Bills will be duking it out all season for the AFC East Division Title.

Week 18 NFL Picks: Dolphins 24 - Bills 38

Well here it is, the game of the week. The Bills fly down to Miami in a winner take the division game. Miami is coming off a loss to the AFC dominant Baltimore Ravens and the Bills just stomped out the New England Patriots, so Buffalo comes in with a little more momentum in this matchup.

The Bills put a beating on the Dolphins back in Week 4 when all the talk was about how explosive the Dolphins are, so that's why we favor the Bills in this game. Even though Miami did defeat the Cowboys, a team above .500; Buffalo did as well, and more convincingly.

Dolphins quarterback Tua Tagovailoa is starting the game a little banged up too, as he left early in last week's blowout loss to the Ravens. Buffalo's quarterback Josh Allen didn't have the greatest passing game against the Pats, but did rush for two of the Bills' scores. And Miami may be without star linebacker Bradley Chubb, so the Dolphins defense might have a hard time containing Josh Allen through the course of the game.