Winning the NBA Draft Lottery is an altering moment for any team in the league.

A franchise could land the best prospect in that year's class, who could be a generational talent. Some picks brought the team to new heights, while others failed to live up to the hype.

With that said, who are the best and worst first-overall picks in this century?

The Worst

5. Markelle Fultz

Picked by the 76ers in 2017, Fultz suffered a shoulder injury, which caused him to forget his shooting form, ultimately failing to make an impact.

However, the 25-year-old is now on an upward trajectory with the Magic, averaging career-highs in almost all facets of his game.

4. Greg Oden

This is more of a case of bad luck than lack of skill. Selected first overall by the Blazers in 2007 over Kevin Durant, Oden only played in 105 regular season games due to several injuries, mainly on his knees.

He only appeared in the league during the 2008-09, 2009-10, and 2013-14 campaigns, being injured in the gap years.

3. Andrea Bargnani

While the Italian enjoyed a decade-long career after going first in the 2006 draft, his production was not on par with the expected numbers among first-overall picks.

After being named in the All-Rookie First Team for Toronto, Bargnani failed to get further accolades.

2. Kwame Brown

Brown was infamous for being chosen by Michael Jordan as the first overall pick for the Wizards in 2001.

Despite lasting 12 seasons in the league, he never averaged double digits in rebounds despite being a 6-foot-11 big man. He played for seven teams, becoming one of the biggest busts ever.

1. Anthony Bennett

Bennett's selection by the Cavs in 2013 was already mind-boggling, and those who were skeptical were right.

He was already out of the league by 2017, bouncing among G League and overseas teams after.

The Best

5. Derrick Rose

The 2008 top selection would have been higher on this list if not for his injuries, but his peak is probably the highest among some names on this list.

Rose became the youngest NBA MVP ever in 2011, leading the Chicago Bulls to the best regular season record and the Eastern Conference Finals that year.

4. Kyrie Irving

Selected by Cleveland in 2011, Irving remains one of the best guards in the NBA today and one of the greatest ball-handlers ever.

He notably hit the biggest shot in Cavs history, nailing a three-pointer, which gave them the lead for good in Game 7 of the 2016 NBA Finals.

3. Anthony Davis

The Pelicans picked Davis in 2012 after a decorated college career in Kentucky, and he brought his dominance to the NBA.

The 30-year-old was selected as one of the league's greatest players in 2021, making the NBA 75th Anniversary Team.

2. Dwight Howard

Selected by the Magic in 2004, Howard was one of the most dominant centers ever during his peak, winning three straight NBA Defensive Player of the Year awards from 2009 to 2011.

His exclusion from the NBA 75th Anniversary Team is subject to criticism from fans, coaches, and analysts.

1. LeBron James

This one is not a debate. Besides Michael Jordan, James is regarded as the greatest basketball player of all time.

The 38-year-old has led three teams to NBA titles, including the Cavaliers, who selected him in 2003.

James became the NBA's all-time leading scorer in February 2023, breaking Kareem Abdul-Jabbar's coveted record.