While the Indianapolis Colts (5-2) were jubilant over being able to spoil Peyton Manning's return to Lucas Oil Stadium by handing the Denver Broncos (6-1) their first defeat of the season by a 39-33 margin, it wasn't without its casualties as wide receiver Reggie Wayne left the game in tears after twisting his knee, and it's now reported that the veteran tore his ACL and will miss the remainder of the season.