Eagles vs. 49ers Week 13: Odds, Spread, Betting Lines, Pick and Preview

San Francisco 49ers v Seattle Seahawks
(Photo : Jane Gershovich/Getty Images) SEATTLE, WASHINGTON - Brock Purdy (#13) of the San Francisco 49ers throws a pass during the third quarter against the Seattle Seahawks at Lumen Field on November 23, 2023 in Seattle, Washington.

The Philadelphia Eagles and the San Francisco 49ers stake their winning streaks on Sunday, December 3, in a Week 13 clash at the Lincoln Financial Field. The Eagles vs. 49ers Week 13 matchup could also be a preview of an NFL playoff matchup.

The San Francisco 49ers are on a three-game streak, the last win coming at the expense of the Seattle Seahawks, 31-13, on Thanksgiving.

On the other end, the Philadelphia Eagles won over the Buffalo Bills in overtime, 37-34. With the two teams among the touted teams to win the Super Bowl, the Eagles vs. 49ers encounter should be a tight contest to watch.

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Eagles vs. 49ers Week 13 Odds

The 49ers are 3-point spread favorites to prevail over the Eagles on Sunday per BetMGM NFL Odds via USA Today. The Moneyline for this matchup is -150 for San Francisco and +125 for Philadelphia. with the over/under at 47.5.

However, the fact that these two teams are Super Bowl favorites means that the Eagles could cover that spread easily. Hence, it all boils down to which team can execute better.

Eagles vs. 49ers Week 13 Preview

The 49ers are on a roll with their offensive machine humming. That was seen when they played the Seahawks with Christian McCaffrey anchoring the San Francisco offense.

That performance led to the 49ers running back winning the FedEx Ground Player of Week 12, the San Francisco Chronicle reported.

The Niners are 3-3 in their last six games and have been playing good defense lately. That showed against Seattle, with the Seahawks finding it tough to get their offensive game going.

Conversely, the Eagles must thread the needle to stave off the Bills. Also, they needed to exert extra effort in the second half after a woeful first half.

However, Philly cannot afford to do that against San Francisco if they want to pull this one off. The Niners are looking for payback against the Eagles after losing last year's NFC Championship game, SI.com reported.

And while most see it as added motivation, 49ers players such as Deebo Samuel are downplaying that notion.

"It's not about revenge. It's another game on the schedule. We're going to treat it like any other game," the Pro Bowl wide receiver said.

Despite other players such as McCaffrey, George Kittle, and Brandon Aiyuk echoing that the Eagles vs. Niners tiff is just another ordinary game, pundits are not buying it. The result will also have dire implications for both teams heading into the postseason.

Eagles vs. 49ers Week 13 Pick

Undoubtedly, the Eagles vs. 49ers Week 13 matchup will be tough to call. The Niners are looking good, and having home-field advantage will factor in.

The Eagles will try to soar but expect the Niners to keep them grounded. The Niners should be able to clip the Eagles' wings for as long as they can sustain their good outings, as seen in their previous NFL assignments.

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